Director of the Genetics Department

Ms. Nesa Barpour

Master of Science in Genetics University of Tabriz, Iran (2018-2021)

genetics@orchidgen.com

 • Thesis: Development of an injectable chitosan-based hydrogel containing nano-hydroxyapatite and alendronate for MSC-based therapy.

Research & Laboratory Skills:

• Molecular Biology Techniques: DNA/RNA extraction, PCR, RFLP, Real-Time PCR,
Gel Electrophoresis
• Cell Biology & Biotechnology: MTT Assay, Cell Culture, Stem Cell Extraction from
Tissue, Flowcytometry
• Tissue Engineering: Bio-Scaffold Fabrication
• Bioinformatics: Primer Design, Data Analysis, R-Programming

 

Publications (Selected):

1.Barpour N, Ghorbani M, Baradaran B, Jodari-Mohammadpour Z, Nejati-Koshki K, AbdollahpourAlitappeh M, Dabbaghi R, Gharibi T. Development of an injectable chitosan-based hydrogel containing nano-hydroxy-apatite and alendronate for MSC-based therapy. International. Journal of Biological Macromolecules. 2024 Jan 27:129737.
2. Gharibi T, Barpour N, Hosseini A, Mohammadzadeh A, Marofi F, Ebrahimi-Kalan A, Nejati-Koshki K, Abdollahpour-Alitappeh M, Safaei S, Baghbani E, Baradaran B. STA-21, a small molecule STAT3 inhibitor, ameliorates experimental autoimmune encephalomyelitis by altering Th-17/Treg balance. International Immunopharmacology. 2023 Jun 1;119: 110160.
3. Safaralizadeh R, Dabbaghi R, Rahmani Sh, Barpour N, Hosseinpourfeizi M, Rajabi A, Baradaran B. The effect of glatiramer acetate, IFNβ-1a, fingolimod, and dimethyl fumarate on the expression of T-bet, IFN-γ, and MEG3 in PBMC of RRMS patients.
4. Mohammadpour ZJ, Mohammadzadeh R, Javadrashid D, Baghbanzadeh A, Doustvandi MA, Barpour N, Baradaran B. Combination of SIX4-siRNA and temozolomide inhibits the growth and migration of A-172 glioblastoma cancer cells. Naunyn-Schmiedeberg’s Archives of Pharmacology. 2023 Apr 24:1-1.
5. Mohammad Javad Khosravanian, Yousef Mirzaei, Ali Hussein Mer, Maryam Keyhani-Khankahdani, Fatemeh Sarina Abdinia, Fatemeh Misamogooe, Zahra Amirkhani, Nader Bagheri, Anna Meyfour, Saeed Jahandideh, Nesa Barpour, Yousef Nikmanesh, Hosein Shahsavarani, Meghdad Abdollahpour-Alitappeh. Nectin-4-directed antibody-drug conjugates (ADCs): Spotlight on preclinical and clinical evidence, Life Sciences, Volume 352, 2024, 122910, ISSN 0024-3205, https://doi.org/10.1016/j.lfs.2024.122910.
6. Hussein Mer Ali, Mirzaei Yousef, Misamogooe Fatemeh, Bagheri Nader, Bazyari Ahmadreza; Keshtkaran Zahra, Meyfour Anna, Shahedi Alireza, Amirkhani Zahra, Jafari Ameneh, Barpour Nesa, Jahandideh Saeed, Rezaei Behzad, Nikmanesh Yousef. Progress of Antibody-Drug Conjugates (ADCs) Targeting c-Met in Cancer Therapy; Insights from clinical and preclinical studies. Drug Deliv. and Transl. Res. 14, 2963–2988 (2024).
7. Yousef Mirzaei, Ali Hussein Mer, Bahia fattah Maran, Leila Omidvar, Fatemeh Misamogooe, Zahra Amirkhani, Nafiseh Javaheri Haghighi, Nader Bagheri, Zahra Keshtkaran, Behzad Rezaei, Farshad Bargrizaneh, Saeed Jahandideh, Nesa Barpour, Hosein Shahsavarani, Ahmadreza Bazyari, Meghdad Abdollahpour‐Alitappeh, Clinical and preclinical advances in PSMA-Directed Antibody-Drug conjugates (ADCs): Current status and hope for the future, Bioorganic Chemistry, Volume 153, 2024, 107803, ISSN 0045-2068
8. Javaher Saleh, Misamogooe Fatemeh, Mirzaei Yousef, Mer Ali Hussein, Bagheri Nader, Saghi Seyyed Amirreza, Dehghani Fatemeh, Bazyari Ahmadreza, Keshtkaran Zahra, Amirkhani Zahra, Meyfour Anna, Jafari Ameneh, Jahandideh Saeed, Barpour Nesa, Rezaei Behzad, Nikmanesh Yousef, Abdollahpour-Alitappeh Meghdad. Antibody-Drug Conjugates beyond HER2-Positive Breast Cancer: A Clinical Perspective Focusing on Hormone Receptor-Positive and TripleNegative Breast Cancer